Medical disclaimer: SnoozeVerdict summarizes what people say about sleep supplements on Reddit. It is not medical advice, and nothing here is meant to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Talk to your doctor or pharmacist before starting a supplement, especially if you are pregnant, take medicines (including sleep or mood medicines), or have a medical condition. Poor sleep that lasts for months, loud snoring or gasping at night, or falling asleep during the day while driving or working needs a doctor, not a supplement. Full disclaimer.
Guide · updated 2026-11-04

Benadryl, ZzzQuil and Unisom: Context Only

Benadryl and ZzzQuil (diphenhydramine) and Unisom SleepTabs (doxylamine) are over-the-counter antihistamine drugs regulated by the FDA as medicines, not dietary supplements. SnoozeVerdict does not score, rank or link to them for purchase.

DrugComments mentioning it
Diphenhydramine (Benadryl, ZzzQuil, many "PM" products)1,451
Doxylamine (Unisom SleepTabs)517

Counts from the 373,690 comments we scanned.

Why context only

Drug dosing and suitability depend on your age and health history, and the label and your pharmacist are the right sources. MedlinePlus lists drowsiness, dizziness and dry mouth among the side effects of diphenhydramine, warns that alcohol adds to the drowsiness, and says it generally should not be used by adults 65 and older except for serious allergic reactions.[MedlinePlus]

If you are comparing supplements for the same sleep problems, see falling asleep and staying asleep.

Still comparing? Browse every sleep supplement we track, sorted by Reddit owner score. For quick shortlists by sleep problem, see which sleep supplements Reddit rates highest. Unsure where to begin? See how to narrow down sleep supplements.

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